Pulmonary Heart Disease

Pulmonary Hypertension (PH)
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Symptoms can become worse when you exercise, which may limit your ability to take part in physical activities. As your condition progresses, you may find it difficult to carry out even everyday activities.

When pulmonary hypertension begins to affect your everyday life, this can have a negative impact on your quality of life and can lead to depression. Untreated pulmonary hypertension can lead to heart failure , which is when your heart muscle is struggling to pump blood around your body.

As well as shortness of breath and tiredness, heart failure can also cause:. Pulmonary hypertension is caused by changes to the pulmonary arteries, the vessels carrying blood from your heart to your lungs. The walls of your pulmonary arteries can become stiff and thickened, or may be blocked by something such as a blood clot.

This makes it harder for your heart to push blood through these arteries, which increases the pressure inside the vessels and results in pulmonary hypertension. There can be many different reasons for the changes to your arteries. The World Health Organization WHO has classified pulmonary hypertension into five different types , depending on the underlying cause:. Pulmonary arterial hypertension PAH is caused by problems with the smaller branches of the pulmonary arteries. In PAH, these changes are usually the core medical problem, rather than a condition that has started somewhere else and then affected the pulmonary arteries.

Unlike the other types of pulmonary hypertension, PAH can therefore be treated directly, while in other cases the underlying cause is treated first. Idiopathic means the cause is unknown. This is rare, affecting one or two people in every million each year. Some cases of PAH can run in families.

It is thought that a particular genetic mutation a change in one of the genes you inherit from your parents can cause PAH. The lack of red blood cells means that haemoglobin, a protein normally found in these cells, is released into the blood. The haemoglobin seeks out and destroys nitric oxide. This is a substance produced by your body and used to widen blood vessels. Without nitric oxide, your blood vessels remain narrow, which increases the blood pressure within them and can cause pulmonary hypertension.

It has been linked to the mother taking non-steroidal anti-inflammatory drugs NSAIDs during the third trimester of the pregnancy week 27 to the birth. Conditions that may also be associated with persistent pulmonary hypertension of the newborn include:. Pulmonary hypertension may sometimes be associated with diseases affecting the left side of your heart which pumps blood around the body.

The left side of the heart is made up of:. Because blood goes from the pulmonary arteries to the lungs and then to the left side of the heart, any problem with the left side of the heart could have a backwards effect on this circuit and affect the pulmonary arteries. This in turn could cause pulmonary hypertension. For example, the mitral valve, which is located between the left atria and left ventricle, can become narrowed.

If this happens, there will be a build-up of blood trying to get through the valve, which will increase blood pressure in the left atria. This could in turn increase pressure in the blood vessels between the lungs and the heart, and then feed back and increase pressure in the pulmonary arteries, leading to pulmonary hypertension. Almost all people with a severe mitral valve condition, and nearly two-thirds of those with a severe aortic valve condition, have pulmonary hypertension.

This includes:. These types of conditions can restrict the amount of oxygen that is getting into the lungs, and therefore into the blood.

Pulmonary Hypertension Related to Left-Sided Heart Failure

Clinical findings associated with pulmonary heart disease include jugular venous distension, prominent v-wave in the jugular venous pulsation, narrow S-2 split or no split slight delay in closure of the pulmonic valve , and, in advanced stages, peripheral edema or ascites. Pulmonary hypertension is high blood pressure in the blood vessels that supply the lungs pulmonary arteries. Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease. Weather conditions were considered confounders and needed to be controlled adequately [ 18 ]. First, there is the right heart-pulmonary vascular interface.

A low level of oxygen in the blood causes the pulmonary arteries to constrict become narrower. Because these vessels are narrower, the blood is squeezed into a smaller space, increasing the blood pressure and resulting in pulmonary hypertension. A foreign object, usually a blood clot, blocking or obstructing a vein, may sometimes cause pulmonary hypertension. It can be difficult to diagnose pulmonary hypertension because the symptoms are similar to other conditions affecting the heart or lungs.

This means there can be a delay of up to three years before you are correctly diagnosed. However, as pulmonary hypertension can be a serious condition, it is important that you see your GP if you experiencing any symptoms. Your GP will ask about:. Several tests may be used to either diagnose pulmonary hypertension or identify an underlying condition that may be causing it. These may be carried out by your GP, or you may be referred to a hospital to have the tests done there.

An echocardiogram is a type of ultrasound scan that can be used to see how well your heart is working. An ultrasound is a procedure that uses high-frequency sound waves to create an image of part of the inside of your body, such as your heart. This can be used to estimate the pressure in your pulmonary arteries. An electrocardiogram ECG is a test that records the rhythm and electrical activity of your heart. Small stickers called electrodes are stuck to your arms, legs and chest and connected with wires to an ECG machine. Every time your heart beats, it produces tiny electrical signals.

Statistics on Pulmonary Heart Disease – Cor Pulmonale

The ECG machine traces these signals onto paper. More about having an ECG. A chest X-ray can be used to look for other causes of your symptoms - for example, scarring in your lungs can also cause shortness of breath. A chest X-ray can also check if your heart is larger than normal - pulmonary hypertension makes the right-hand side of your heart work harder, causing it to become enlarged.

Pulmonary Hypertension

Lung function tests, also called breathing tests, assess how well your lungs work. These tests measure how quickly you can move air in and out of your lungs, how much air they can hold and how well they transfer oxygen into and remove carbon dioxide from your blood. The tests require you to breathe in and out of a lung function machine, and the information collected will help to diagnose different lung diseases.

Exercise tests involve carrying out some form of exercise while checking your symptoms. For example, you may need to walk for six minutes, either on a treadmill or up and down a corridor, while your heart rate and blood pressure are monitored. This can be useful in determining any underlying causes for your symptoms. A ventilation scan measures the amount of air and the blood flow in your lungs.

This can be used to look for blood clots in your vessels that may be causing pulmonary hypertension. The tests above may all suggest pulmonary hypertension, but the diagnosis is only confirmed by measuring the blood pressure in:.

In right-heart catheterisation, a thin, flexible tube called a catheter is inserted into a vein in your neck, arm or groin. This catheter is fed through into the right side of your heart and into your pulmonary arteries. As well as measuring the blood pressure, the catheter can be used to measure:. If the pressure in your pulmonary arteries is above a certain level, you will be diagnosed with pulmonary hypertension. If the above diagnostic tests reveal an underlying cause, you will be diagnosed with a particular type of pulmonary hypertension. If no cause is found, you will be diagnosed with idiopathic pulmonary arterial hypertension.

If your pulmonary hypertension is caused by an underlying condition, your treatment will focus on tackling it. If the cause is treated early, it may be possible to prevent permanent damage to your pulmonary arteries the blood vessels supplying your lungs.

Pulmonary hypertension

If you have pulmonary arterial hypertension PAH , you will be referred for treatment at a centre that specialises in PAH. A number of different medicines can be used to treat PAH and other types of pulmonary hypertension. You will usually be started on conventional therapy or background therapy, and your treatment will then be changed or increased as necessary. Further treatment is called targeted therapy. PAH can increase your risk of venous thromboembolism, which is when a blood clot forms in a vein and then breaks free.


Pulmonary heart disease, also known as cor pulmonale, is the enlargement and failure of the right ventricle of the heart as a response to increased vascular. Pulmonary heart disease (PHD) refers to altered structure or function of the right ventricle occurring in association with abnormal respiratory function. Although.

The clot can become trapped in a blood vessel, blocking the vessel and the blood supply. If this blocks one of the blood vessels supplying your lungs, this is called a pulmonary embolism. Anticoagulant medicines reduce the ability of the blood to clot. Taking anticoagulants, such as warfarin, may therefore reduce your risk of venous thromboembolism.

Diuretic medicines are used to remove excess fluid from the body by increasing the production and flow of urine.

Pulmonary heart disease, unspecified

Diuretics may be used in pulmonary hypertension to treat any fluid retention and swelling oedema. Diuretics can also disrupt your levels of electrolytes minerals in your blood, such as potassium and affect your kidney function. Because of this, your kidneys and blood will be monitored while you are taking diuretics.

If you have low oxygen levels in your blood, you may need to be treated with oxygen. This involves inhaling air that has a higher amount of oxygen in it than normal. This increases the amount of oxygen in your blood and should improve your symptoms.

Pulmonary Diseases and the Heart

If your pulmonary hypertension leads to heart failure, you may be treated with digoxin. They work by relaxing the muscles that make up the walls of your arteries. MedlinePlus : Cardiovascular disease heart I00—I52 , — Angina pectoris Prinzmetal's angina Stable angina Acute coronary syndrome Myocardial infarction Unstable angina. Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Tachycardia-induced Restrictive Loeffler endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular dysplasia. Accelerated idioventricular rhythm Catecholaminergic polymorphic Torsades de pointes.

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Pulmonary Hypertension Overview - Mayo Clinic

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